New U.S. drug prices doubled amid a shift toward treating rare diseases
Drugs being explicitly developed to treat rare diseases are getting more expensive.
The INFORMS Analytics+ Conference showcased how companies are turning advanced analytics and AI into measurable operational results
In most emergency departments, beds are a hot commodity. But some patients don’t actually need a bed for their treatment – and accurately identifying those people is a low-lift but effective way to increase efficiency without sacrificing care quality, finds a study recently published in the journal Management Science.
The researchers developed a simple decision tree, informed by mathematical and machine learning models, to help staff decide whether a patient truly needs a bed or can be routed to a “vertical processing pathway” – that is, an area where they can be treated sitting up. Many hospitals already have such an area but don’t necessarily have a systematic way to decide which patients are treated there.
American teenagers start their school day too early.
Medical experts have been clear for years: sleep cycle changes during puberty make it hard for teenagers to learn in the early morning. Later school start times have been linked to better sleep, improved mental health, stronger academic performance and even safer driving.
Most school district leaders know about this problem and care about fixing it. But changing the schedule can feel operationally impossible.
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Drugs being explicitly developed to treat rare diseases are getting more expensive.
Trade groups have unsuccessfully urged President Donald Trump to exempt medical supplies and devices. One Minneapolis hospital shows the complexity of this supply chain.
Old technology is behind the recent ongoing delays and cancellations at Newark Liberty International Airport, but newer technology will be an important part of the solution.
With seemingly no limit to the demand for artificial intelligence, everyone in the energy, AI, and climate fields is justifiably worried. Will there be enough clean electricity to power AI and enough water to cool the data centers that support this technology? These are important questions with serious implications for communities, the economy, and the environment.
BALTIMORE, MD, May 24, 2025 – Most anti-human trafficking efforts focus on breaking up sex sales; however, new research in the INFORMS journal Manufacturing & Service Operations Management is turning its attention to where trafficking truly begins – recruitment. Using machine learning to analyze millions of online ads, researchers at the University of Pennsylvania have uncovered patterns that link deceptive job offers to sex trafficking networks. By mapping the connections between recruitment and sales locations, the study reveals a hidden supply chain – one that can now be exposed and interrupted earlier in the trafficking process.

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